Pediatric brain tumors: management strategies
نویسندگان
چکیده
منابع مشابه
Pediatric Brain Tumors
Primitive neuroectodermal tumors (PNET) of the brain include medulloblastoma (MB) and central nervous system primitive neuroectodermal tumor (CNS PNET) subtypes, which share histological features yet differ at the genomic level and in clinical outcome. Delineation of the genetic anomalies between PNET subtypes is a current challenge for establishing effective targeted therapeutic strategies aga...
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Pediatric central nervous system primitive neuro-ectodermal brain tumors (CNS-PNETs) are rare tumors with ill-defined biological features. In this issue of Cell, Sturm et al. used state-of-the-art methods to interrogate these tumors' biology. Their integrated molecular analyses led them to propose a new molecular classification, with four new entities identified, that should get oncologists' at...
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Malignant brain tumors are the most common cause of solid cancer death in children. New targeted therapies are vital to improve treatment outcomes, but must be developed to enable trafficking across the blood brain barrier (BBB). Since activated T cells cross the BBB, cancer immunotherapy can be harnessed to unlock the cytotoxic potential of the immune system. However, standard of care treatmen...
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UNLABELLED Background and Need for Novel Biomarkers: Brain tumors are the leading cause of death by solid tumors in children. Although improvements have been made in their radiological detection and treatment, our capacity to promptly diagnose pediatric brain tumors in their early stages remains limited. This contrasts several other cancers where serum biomarkers such as cancer antigen (CA) 19-...
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Background: spinal tumors constitute about 8 % of central nervous system tumors. They are not uncommon in pediatric population. Objectives: The author reviews his experience in surgical aspects and techniques of management of this subtype of pediatric tumors. Patients and Methods: Medical records of twenty five pediatric patients with spinal tumors admitted to Children's Cancer Hospital-Egypt (...
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ژورنال
عنوان ژورنال: Neurosurgical Focus
سال: 2005
ISSN: 1092-0684
DOI: 10.3171/foc.2005.18.6.1